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Facilities

Kaifeng Darui Pharmaceutical Co., Ltd. operates ​GMP-certified facilities​ in the Kaifeng Fine Chemical Park, equipped with advanced technology to ensure precision, compliance, and sustainability in producing ​veterinary APIs, ​pharmaceutical intermediates, and ​food additives.

Core Production Equipment & Systems

​1. GMP-Certified Manufacturing Infrastructure​

  • ​Synthesis & Refining Workshops​
    • ​700㎡ production area​ with two independent lines (synthesis + refining/packaging).
    • ​D-grade cleanrooms​ (ISO 8 equivalent): Air purification systems, color steel partition walls for contamination control.
    • ​150t/d wastewater treatment: Eco-friendly recycling compliant with China’s green chemical standards.
    • ​RCO (Regenerative Catalytic Oxidation): VOC emissions reduction for sustainable operations.

​2. Precision Processing Equipment​

  • ​Distillation & Reaction Systems: High-efficiency distillation towers for API purification.
  • ​Drying & Crystallization:
    • Bromonitro alcohol crystallization dryers (patented).
    • Double-cone vacuum dryers for heat-sensitive compounds.
  • ​Automated Control: Closed-loop dosing systems and corrosion-resistantmother liquor recovery.

Quality Control & Analytical Laboratories

​1. Advanced Testing Instruments​

  • ​Chromatography:
    • Shimadzu HPLC for impurity profiling.
    • Shanghai Yichun GC and FTIR.
  • ​Precision Measurement:
    • Electronic analytical balances (±0.1mg accuracy).
    • UV-Vis spectrophotometers, melting point analyzers.
  • ​Stability Testing: Climate-controlled chambers for ICH-compliant shelf-life studies.

​2. Utility & Support Systems​

  • ​Purified Water Systems: USP-grade water for production and cleaning.
  • ​HVAC & Air Handling: HEPA-filtered cleanroom air conditioning for temperature/humidity control.
  • ​Warehousing: Climate-monitored storage for raw materials, finished goods, and hazardous substances.

Compliance & Certifications

  • ​Veterinary drug GMP certification: Full compliance with China’s Veterinary Drug Production Quality Management standards.
  • ​18 API GMP Certificates: Issued by Henan Province’s Department of Agriculture (November 2024).
  • ​Utility Patents: 12+ patented systems (e.g.,Vacuum distillation anti-corrosion device, bromonitro alcohol recovery devices).

Sustainable & Scalable Operations

  • ​Waste Minimization: Closed-loop solvent recovery and RCO for 95%+ VOC elimination.
  • ​Energy Efficiency: Automated controls reduce energy consumption by 20% vs. industry benchmarks.
  • ​Scalability: Modular facility design supports capacity expansion (current output: 6,000+ tons/year).

​Why Partner with Darui Pharma?​​

  • ​End-to-End Capabilities: From R&D-scale synthesis to GMP production.
  • ​Global Standards: Equipment validated for FDA/EMA-compliant exports.
  • ​Technical Support: 20+ engineers for equipment maintenance, process optimization, and troubleshooting.

​Contact Us​ for OEM/ODM projects, equipment specifications, or facility audits.


Kaifeng Darui Pharmaceutical Co., Ltd.

Kaifeng Darui Pharmaceutical Co., Ltd.

Dedicated to high-end pharmaceutical raw materials, food additives, and intermediates.

About Us

Kaifeng Darui Pharmaceutical Co., Ltd., established on June 19, 2020, with a registered capital of 27 million RMB, is a high-tech enterprise located in the Kaifeng Fine Chemical Industrial Park. We focus on the R&D, production, and sales of high-end pharmaceutical raw materials, food additives, and intermediates.

We are a professional GMP-certified manufacturer of veterinary non-sterile APIs, strictly adhering to veterinary GMP requirements in design and construction. Our facility boasts a clean production environment and a rational layout.

We uphold the concept of green development, emphasizing talent and team building to achieve sustainable and healthy growth.

Financial Highlights:

  • 2023 Total Output Value: 44 million RMB, Tax Contribution: 1.45 million RMB.
  • 2024 Total Output Value: Over 60 million RMB, Tax Contribution: 2 million RMB.

Company Philosophy: "Survive by quality, root in talent; develop by technology, benefit from management." We persistently pursue excellent quality and a perfect brand and corporate image.

Research & Development

Since our inception, we established a dedicated technical team for R&D and technology introduction. Currently, we employ over 100 staff, with more than 20 R&D professionals (over 20% of workforce). Over 70% hold college degrees or higher, including 2 senior engineers, 2 associate professors, 1 lecturer, and 4 intermediate engineers.

We possess an independent R&D center (320 sq meters) with professional chemical laboratories and dedicated testing/analysis units. Our equipment includes HPLC, GC, UV-Vis Spectrophotometers, analytical balances, moisture analyzers, etc.

We collaborate closely with domestic universities and research institutions like Henan Academy of Sciences Chemical Research Institute Co., Ltd., Pingdingshan University, and Xinxiang Medical University to foster industry-university-research cooperation.

Facilities

Our plant is designed and built according to "Veterinary Drug Manufacturing Quality Management Standards".

  • Non-sterile API workshop (700 sq meters) with synthesis and refining/drying/packaging sections.
  • Two production lines with separate air purification systems; clean areas meet Class D standards.
  • Standardized production workshops, distillation equipment, 150 t/d wastewater treatment facility, and RCO exhaust gas treatment unit.
  • Water production equipment and air conditioning/purification systems.
  • Warehousing: Raw/auxiliary material, finished product, packaging material, and special management finished product warehouses.

Qualifications & Honors

  • High-tech Enterprise Certification (2023).
  • Henan Province Innovative Small and Medium-sized Enterprise (Dec 2022).
  • Kaifeng City Alkane Bromination Product Engineering Technology Research Center (2023).
  • Loving Charity Enterprise Title (Jan 2023).
  • Kaifeng Pharmaceutical Industry Association Council Member (Since 2021), Chairman Yang Xiaoke appointed as Council Director (Jan 2024).
  • Veterinary Drug Production License and 18 API GMP Certificates from Henan Provincial Department of Agriculture and Rural Affairs (Nov 2024).

Intellectual Property

We emphasize technological innovation and transformation. As of the report date, we hold 12 utility model patents, with 4 applications pending. These patents enhance our independent innovation capabilities and promote the transformation of scientific achievements.

Products & Services / Cooperation

Focus Areas:

  • Fine Chemicals & APIs
  • Food Additives
  • Fine Chemical & Pharmaceutical Intermediates

Areas for Cooperation:

  • Development of new veterinary and pet APIs.
  • Development of new food additives.
  • Cooperation on key production technologies, development and application of fine chemicals and pharmaceutical intermediates.

Future Outlook & Industry Prospects

As a certified High-tech Enterprise, we aim to standardize R&D project management, enhance innovation, and follow the growth path of quality SMEs (Sci-tech SME, Innovative SME, "Specialized, Refined, Unique, New" SME, Sci-tech Little Giant).

Key Development Directions:

  • Leveraging alkane bromination technology, establishing a national-level R&D, demonstration, training, pilot testing, and cooperation base.
  • Strengthening high-value-added biomedical fine products based on existing antiviral and anthelmintic products through R&D and university collaborations.
  • Continuing focus on veterinary APIs, capitalizing on the growing pet market, expanding livestock farming needs, and increasing international competitiveness and export opportunities for Chinese veterinary APIs.

Three-Year Goal (Targeting 2025): Achieve 100 million RMB in production and sales value, increase R&D investment to 20 million RMB, develop 2-3 new products annually, and attain the "Specialized, Refined, Unique, New" enterprise status.

© Kaifeng Darui Pharmaceutical Co., Ltd. All rights reserved.

Contact Us

Address: Kaifeng Fine Chemical Park, Henan, China

Tel: +86-13837178289

Email: [email protected]